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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
8.18
Human Site:
S71
Identified Species:
13.85
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
S71
R
F
I
G
R
R
Q
S
L
I
E
D
A
R
K
Chimpanzee
Pan troglodytes
XP_508221
618
67613
S161
R
F
I
G
R
R
Q
S
L
I
E
D
A
R
K
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
G62
N
E
T
A
T
E
S
G
K
T
A
V
V
F
S
Dog
Lupus familis
XP_855547
495
55650
L66
S
S
E
P
G
D
L
L
E
A
A
V
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
P65
A
A
V
A
S
A
E
P
G
N
P
L
E
A
V
Rat
Rattus norvegicus
P04177
498
55948
P65
A
A
V
A
S
S
E
P
G
N
P
L
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
P80
R
L
L
S
L
P
A
P
V
H
T
W
L
R
C
Chicken
Gallus gallus
P70080
445
51121
R17
D
H
A
P
E
R
G
R
T
A
I
I
F
S
L
Frog
Xenopus laevis
Q92142
481
55388
R52
Y
S
E
N
V
C
E
R
G
K
A
S
V
I
F
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
E61
A
E
A
A
G
L
S
E
Q
I
V
F
E
E
S
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
S48
R
D
G
F
G
F
G
S
G
S
E
E
K
L
D
Fruit Fly
Dros. melanogaster
P18459
579
65977
Y133
Q
Q
P
T
K
N
D
Y
G
L
T
E
D
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
G28
A
D
V
N
A
D
I
G
K
T
T
I
V
F
T
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
S67
I
E
D
A
R
R
E
S
T
R
S
S
L
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
13.3
6.6
0
6.6
20
0
N.A.
0
20
P-Site Similarity:
100
100
0
20
N.A.
13.3
13.3
N.A.
26.6
6.6
6.6
6.6
26.6
26.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
15
15
36
8
8
8
0
0
15
22
0
15
15
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
15
8
0
0
15
8
0
0
0
0
15
8
8
8
% D
% Glu:
0
22
15
0
8
8
29
8
8
0
22
15
22
15
8
% E
% Phe:
0
15
0
8
0
8
0
0
0
0
0
8
8
15
8
% F
% Gly:
0
0
8
15
22
0
15
15
36
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
15
0
0
0
8
0
0
22
8
15
0
8
15
% I
% Lys:
0
0
0
0
8
0
0
0
15
8
0
0
8
8
15
% K
% Leu:
0
8
8
0
8
8
8
8
15
8
0
15
15
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
0
8
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
8
15
0
8
0
22
0
0
15
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
15
0
8
0
0
0
0
0
0
% Q
% Arg:
29
0
0
0
22
29
0
15
0
8
0
0
0
22
0
% R
% Ser:
8
15
0
8
15
8
15
29
0
8
8
15
8
8
15
% S
% Thr:
0
0
8
8
8
0
0
0
15
15
22
0
0
0
8
% T
% Val:
0
0
22
0
8
0
0
0
8
0
8
15
22
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _